Oral medications are in development to provide alternative to injectables such as Wegovy that must be kept in fridge

Newly developed weight loss pills could have a big impact on tackling obesity and diabetes in low- and middle-income countries, experts have said.

Weight loss jabs such as Wegovy and Mounjaro, that contain the drugs semaglutide and tirzepatide respectively, have become popular in countries including the UK after trials showed they can help people lose more than 10% of their body weight . Medications containing semaglutide and tirzepatide can also be used to help control diabetes.

Victoria McCloud brings action against UK for infringement of her human rights after ruling on biological sex

Britain’s first transgender judge is taking the UK to the European court of human rights over the supreme court’s ruling on biological sex.

The UK supreme court ruled earlier this month that the terms “woman” and “sex” in the Equality Act referred only to a biological woman and to biological sex, with subsequent guidance from the equalities watchdog amounting to a blanket ban on trans people using toilets and other services of the gender they identify as.

North Yorkshire coast
With its swooping whale, snapping seal and mischievous god, the artist’s tricksy new work, made with Coralie Turpin, is just one of the fun-filled additions to Scarborough’s reinvigorated Wild Eye coastal art trail

It would be too simple to say that Jeremy Deller is interested in history. It would be more accurate to say he’s interested in things that aren’t there; or things that were once there; or perhaps things that could have been there. Protesting miners, deceased soldiers, inflatable sites of pagan worship have all been created or re-created by the Turner prize-winning artist, who has now turned his hand to a “speculative [Roman] mosaic” for Scarborough’s Wild Eye coastal art and nature trail.

Created with sculptor Coralie Turpin , Deller’s mosaic is a “semi-trick” – a suggestion of a Roman masterpiece that has been uncovered on the shores of the seaside town with genuine Roman history. On the cliffs above the work sits the remains of a Roman signal station, and the mosaic is fragmented and inaccurate as if made from memory rather than a photograph, generating a sense of authenticity. “In 100 years’ time – or whenever – when this is all underwater and it is rediscovered, someone will think ‘Fuck, there was a Roman villa here,’” says Deller.

From the Premier League to MLS and the NFL, huge stadiums with gargantuan costs are a symptom of elite sport’s unrealistic promises

“Nil satis nisi optimum,” boasts the motto of Everton FC: “Nothing but the best is good enough.” Performances on the pitch over the past few seasons have suggested otherwise (what’s Latin for “Anything to stay up will do?”) but in the form of the sparkling new stadium at Bramley-Moore Dock, which will replace Goodison Park as Everton’s permanent home from the start of next season, the club now has tangible proof that its historic aspiration to excellence is at last being met.

Based on the renderings and early footage of its interior, Everton Stadium (it will be a while before that bland placeholder is draped in the capitalist rococo of the “TeslaDome” or “Open AI’s ChatGPT Arena” or “Palantir Presents Bramley-Moore Dock”) appears to be a pleasingly raked and compact arena that should retain at least some of the raucousness of Everton’s old home. The stands are at the steepest pitch that regulations will allow, sightlines are unobstructed from every seat, and judging from the promotional videos, fans will never be more than 50 metres from either a toilet or a scouse pie, which seems like a key metric of success for any stadium in Liverpool.

Scientists on Union glacier in Antarctica fear the region is reaching a dangerous tipping point

• Words and photographs by James Whitlow Delano

Every time Dr Ricardo Jaña crosses the turbulent seas that separate Chile from Antarctica, it feels like his first time. The glaciologist at the Chilean Antarctic Institute (Inach) has sailed each year for 12 years through the Drake Passage, where the prevailing westerly winds, unimpeded by any land mass, raise the waters in chaotic waves that lash his boat.

“I feel powerless and resigned to the forces of nature,” says Jaña, who is the research chief at the Union Glacier Joint Scientific Polar Station.

Jaña skis around the glacier making global navigation satellite system measurements

It’s better to buy from a plant shop, but these tips will improve the survival rate of herbs and other supermarket plants

What’s the problem?
Should I buy houseplants from the supermarket? I’ve had mixed results – some have thrived, but others (especially herbs) have barely survived the journey home.

Diagnosis
While supermarkets often offer attractive prices and convenience, plants are treated more like fast-moving stock than living things. They are often displayed under harsh lights and watered inconsistently. Herbs, in particular, are usually grown fast in overcrowded pots and intended for short-term use.

Company says consumer confidence could deteriorate further as countries face risk of recession

• Business live – latest updates

Shares in the owner of Primark fell after the budget clothing chain posted a sharp drop in UK sales and lost market share, as the company warned that consumer confidence was likely to worsen further amid Donald Trump’s trade wars.

Associated British Foods (ABF), which also owns a sugar business and food brands such as Ryvita and Kingsmill, said several countries could slide into recession as a result of US trade policy.

This was a vote against delusions of a ‘51st state’ and economic warfare, rather than an endorsement of the Liberals’ policies

Yesterday, as Canadians went to the polls, US president Donald Trump suggested that if Canada became part of America , they could vote for him instead. But in truth, Canada becoming the 51st state wasn’t a prerequisite for Canadians to vote on Trump. It was Trump who set the stakes of this election anyway, beginning almost as soon as he took office. His threats against Canada , both economic and existential, were the backdrop of this campaign. An unexpected crisis on our doorstep.

And now, the Liberal party, led by Mark Carney, has won a fourth term in office , a result that would have seemed unthinkable just a few months ago, before Trump’s unprecedented intervention.

Colin Horgan is a Toronto-based writer and a former speechwriter for Justin Trudeau

Labour chair Ellie Reeves says the Tories are doing nothing in local election campaigning as Kemi Badenoch defends approach

Good morning. There are two days left until the local elections in England and, conveniently perhaps for Labour campaigners, the government’s main announcement is about a plan to stop sex offenders claiming asylum in the UK. Rajeev Syal has the details here.

The government is announcing this now because it will change the law via an amendment to the border security, asylum and immigration bill, which has already finished its committee stage in the Commons and will soon get its report stage (the last chance for an amendment before the bill goes to the Lords). Immigration policy is not a matter for local authorities, but Labour will still be hoping that today’s headlines might be at least marginally helpful as people think about how to vote.

No, I don’t. We had a historic defeat last year, and it’s going to take some time for us to get back on track. I am working to rebuild public trust, letting the country know that the Conservative party is under new leadership. But as we saw with previous oppositions, it took 14 years, 13 years and 18 years to come back. I’ve only been leader for six months. It’s going to take a while to fix the problems which we had from last year.

The Tories aren’t doing anything. [Tory MP] Esther McVey basically said the Tories should sit it out and let Reform win, and we’re seeing that on the ground.

They’re not doing any work on the ground at all, it looks like they’re just gifting it to Reform.